At INTERCEPT, we are transforming the landscape of Crohn’s disease research by shifting from reactive symptom management to proactive early detection and prevention. Our groundbreaking approach leverages biomarkers - measurable substances found in body fluids that can signal the presence of the earliest stages of the disease before it clinically manifests - to identify individuals at risk before symptoms develop, enabling timely and effective interventions that could stop the disease before it starts.
Objectives
Our mission is clear: make Crohn’s disease a manageable – or even preventable - condition by identifying and validating biomarkers that predict disease onset and progression.
To achieve this, we aim to:
By revolutionising Crohn’s disease detection, we are setting a new standard. One that could extend beyond Crohn’s to other chronic inflammatory diseases.
Our Approach
To bring this vision to life, INTERCEPT is launching a multinational study with partners in the United States, Europe and South Korea, combining cutting-edge science, advanced technologies and global expertise.
Our approach consists of three key elements:
- Biomarker Validation & Risk Scoring
- Recruiting 10,000 first-degree relatives of Crohn’s patients across seven European countries.
- Developing a blood risk score to identify high-risk individuals before symptoms appear.
- Preventative Intervention Trial
- Selecting 80 high-risk participants for an innovative prevention trial.
- Using proven medical treatments to intercept disease progression at the preclinical stage.
- Global Collaboration & Infrastructure
- Partnering with top universities, research centres and industry leaders across Europe, North America and South Korea.
- Building a sustainable research framework to accelerate future biomarker-driven disease interception.
Impact & Vision
Our research is set to drive major advancements in the fight against Crohn’s disease and beyond.
With INTERCEPT, our vision is clear: a future where Crohn’s Disease is not only manageable but potentially avoidable.
Together, we can change lives, redefine healthcare and pioneer a future without Crohn’s Disease.